A new study published in the European Medical Journal has revealed a startling connection between upper gastrointestinal (GI) issues and Parkinson’s disease (PD). According to UAE doctors, patients with digestive issues like ulcers in the oesophagus or stomach are 76% more likely to develop PD later in life. The study confirms a growing body of research linking the gut and the brain through the gut-brain axis.
Dr. Mohamed Ahmed Elshobary, from Thumbay University Hospital, explains that the gut and brain are interconnected by a network of neurons, and issues in the digestive system can impact brain function. Inflammation in the gut, for example, is associated with neurodegenerative diseases like Parkinson's. Digestive issues can lead to a reduction in the production of neurotransmitters, such as serotonin, crucial for cognitive functions and mood regulation.
The study also highlights that early symptoms like constipation and dysphagia may precede the neurological symptoms of Parkinson’s. Dr. Amal Upadhyay, Consultant at Medcare Hospital Sharjah, points out that recognizing these GI symptoms could allow for earlier diagnosis and management of PD.
Doctors stress the importance of maintaining gut health through a proper diet, rich in fresh, probiotic foods, and avoiding overuse of medications like NSAIDs, which may harm the gut lining. Dr. Srinivas Patnaikuni of Prime Hospital further emphasizes that gut microbiota imbalances could trigger abnormal signaling to the brain, supporting the hypothesis that Parkinson’s may originate in the gut for certain patients.
With growing awareness of the gut-brain connection, experts urge proactive management of gastrointestinal issues to mitigate risks of neurodegenerative diseases like Parkinson’s.
